mikoto misaka let me tell why thats bullshit

It (Extraordinary Genius) does mean she will plan her actions enough to never create an easy breach in her defenses for Tsuna to attack through. Tsuna also won against some opponents who has advantage in range, such as berserk Gola Mosca which he can dodge its missiles and enerygy shots spam without problem, or Xanxus who is an combar expert on both close and far ranges and has far more experience on combat than him. He can still generate barrier from his flame to help him block her attacks. Not to mention that his Hyper Intuition can also help him to avoid Mikoto's attack in some degree. And Tsuna's mobility is far greater than him. Even a clumsy character like Leviathan can dodge a real lightning. But I think that he should be able to avoid and get close her. Tsuna has disadvantage in range and he need to get close Mikoto first.

While Mikoto's knowledge about Tsuna strongest attack (which should be Zero point Breakthrough: First Edition) seem not to help her much since even Tsuna's normal punch or kick is enought to one-shot glass cannon like her. Misaka only has one 7-C attack with lightning strikes.

Mikoto misaka let me tell why thats bullshit